Careers

Program Manager / Director

ABOUT PH

Picture Health creates multimodal AI imaging biomarkers that accelerate oncology drug development. Our proprietary Px™ Platform integrates next‑generation radiomics and pathomics to extract biologically interpretable features from routine scans—powering patient stratification, early response assessment, and predictive endpoints. We partner with leading biopharma and CROs to bring better therapies to patients faster, with work presented at major meetings (e.g., ASCO) and supported by a growing body of peer‑reviewed research. We’re a fast‑growing, mission‑driven team headquartered in Cleveland with a hybrid/remote team, competitive compensation, top‑tier benefits, and a Pledge 1% commitment. If you’re passionate about using AI to help cancer patients, come build with us.

WHAT YOU’LL DO

  • Own end‑to‑end delivery of pharma programs—from project planning and kickoff through analyses, milestones, and final presentations—ensuring quality, clarity, and on‑time execution.
  • Be the face of Picture Health with translational medicine and clinical development partners: set expectations, run recurring touchpoints, and turn feedback into clear next steps.
  • Provide scientific direction and create analysis plans for advanced AI biomarker development/application; align endpoints, subpopulation and sensitivity analyses, and statistical approach with sponsor priorities.
  • Turn results into narratives—create crisp deliverables (reports, data packages, exec‑ready slides) that help internal champions socialize and "sell" biomarker value across Biostats, Clin Dev, Regulatory, and Commercial.
  • Speed the work to startup pace by aggressively unblocking data/contract flows, tightening iteration cycles with our research team, and driving faster decision‑making across sponsors and vendors.
  • Scale our delivery model by refining playbooks, templates, and engagement norms—and by providing direct product feedback (platform features, data ops, integrations) that reduces cycle time and increases repeatability.
  • Coordinate cross‑functional execution with AI/ML, biostats, data engineering/ops, and external vendors (CROs, labs, imaging partners) to keep scope aligned and issues resolved.
  • Support study design—review protocols and amendment language for biomarker objectives; advise on data/specimen needs, stratification, and feasibility.

REQUIRED QUALIFICATIONS

  • Degree in a relevant scientific/quantitative field (e.g., Molecular Biology, Biology, Biomedical Engineering, Biostatistics, Bioinformatics, Applied Mathematics). PhD preferred.
  • 3–8 years in a global pharmaceutical sponsor environment within Translational Medicine and/or Clinical Development, having collaborated across the complex matrix of functions touching drug development from R&D through Commercial.
  • Understanding of biomarker evidence standards (e.g., fit‑for‑purpose validation) and stakeholder expectations across Biostats, Clin Dev, Regulatory, Medical Affairs.
  • Oncology experience with hands‑on analysis/interpretation of clinical‑trial datasets (Phase I–III and/or retrospective/RWD), including endpoints, subgroup/stratification, and sensitivity analyses.
  • Proven ability to present to senior management and communicate complex methods/results to both technical and non‑technical stakeholders.
  • Strong program/project leadership across scope/timelines/budget, with a bias for action and excellent written/verbal communication.

IDEAL QUALIFICATIONS

  • Consulting experience (life‑sciences strategy, R&D/clinical development consulting, or internal "corporate consulting"/program leadership in pharma).
  • Demonstrated client‑service ownership of consulting‑style deliverables (analysis plans, interim/final reports, data transfers, executive narratives).
  • Familiarity collaborating with CROs, specialty labs, imaging vendors, and data providers.
  • Working fluency with biostats/ML teams (hands‑on statistical analysis or coding not required).
  • Start‑up or new‑program build experience; change management and playbook creation.

WHAT SUCCESS LOOKS LIKE (FIRST 6 MONTHS)

  • Multiple sponsor programs delivered on time with clear value narratives enabling internal adoption.
  • Cycle time from data receipt to insight materially reduced via tighter sponsor/vendor coordination and product/platform feedback.
  • Reusable templates/checklists established for analysis plans, governance updates, and executive summaries; incorporated into our platform and delivery playbooks.

LOCATION & WORK STYLE

  • Remote‑friendly (U.S.) with periodic on‑sites and sponsor travel; HQ in Cleveland, OH.
  • Compensation: $135,000–$180,000 base salary plus meaningful equity.
  • Full‑time; title/level flexible (Program Manager/Senior PM/Director) based on experience.

HOW TO APPLY

Fill out the form below or email your resume and a brief note articulating your most relevant expertise to careers@picturehealth.com.

Fill out the form to send your application

Picture Health is Hiring

As part of our team, you’ll have the opportunity to work with innovative colleagues and contribute to shaping the future of cancer care. We offer a hybrid/remote work, competitive salary, top-tier health benefits, and regular on-site events. Our commitment to making a positive impact extends beyond our work, as we’re a proud member of the Pledge 1% movement.

We’re growing fast and hiring for different positions across the company. Click on any open roles below to see a full job description. If you’re interested in another position or have other questions, please email us at careers@picturehealth.ai

Freelance Full Time Internship Part Time Temporary ALL

Note: Picture Health does not accept unsolicited resumes or profiles from recruiters. We may use any information submitted and no fees will be paid without prior written contract.